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Iowa State University Postdoc Research Associate in Ames, Iowa

Position Title:Postdoc Research Associate

Appointment Type:Post Doc/Trainee

Job Description:Summary of Duties and Responsibilities:

An NIH funded postdoctoral position is available in the MacIntosh lab to study the role of lysosomal proteins in endocytosis and lipid transport in Drosophila. We are also interested in the connection between these processes and lysosomal disorders, including Parkinson’s disease. The laboratory uses a multidisciplinary approach, including microscopy, metabolomics, and transcriptomics analyses to uncover the metabolic pathways that control acidification of the endocytic pathway, the role of endocytic processes in interorgan lipid transport, and homeostasis. For recent publications supporting this project and the open questions that we want to address, please see Chaudhry et al. 2022. Autophagy 18 (10), 2443-2458; Handy et al. 2024. Autophagy 20 (2), 437-440. In addition, there will be opportunities for gaining mentorship experience via helping to train junior investigators in the group and for developing projects contributing to their own related areas of interest to start an independent career.

We are seeking a motivated individual with a Ph.D. in biochemistry, cell and molecular biology, or related areas. Experience in Drosophila molecular genetics is preferred. Candidates should have a strong interest and background in one or more of the following: lipid biology, molecular biology, imaging, bioinformatics and systems biology, cell biology, and/or animal models of disease. The successful applicant will have excellent organizational and communication skills, a commitment to detail, the ability to work both independently and as part of a larger team, and a demonstrated capacity to perform creative and original research.

T o guarantee full consideration, applications must be received by 7/15/2024

Required Minimum Qualifications:

PhD

Preferred Qualifications:

  • Experience in Drosophila dissections and molecular genetics strongly preferred.

  • Experience analyzing metabolomics and/or transcriptomics datasets.

  • Experience with expression (E. coli, yeast, and insect cells) and purification of proteins.

  • Experience with confocal microscopy.

  • Familiarity with lipid metabolism.

Proposed Start Date:August 12, 2024

Proposed End Date or Length of Term:August 11, 2026

Number of Months Employed Per Year:12 Month Work Period

Time Type:Full time

Application Instructions:

To apply for this position, please click on “Apply” and complete the Employment Application. Please be prepared to enter or attach the following:1) Resume/Curriculum Vitae2) Letter of Application/Cover LetterIf you have questions regarding this application process, please email employment@iastate.edu or call 515-294-4800 or Toll Free: 1-877-477-7485.Why Choose ISU?Iowa State Postdocs enjoy comprehensive health and work-life benefits, including medical and dental; as well as:• Retirement benefits including defined benefit and defined contribution plans• Generous vacation, holiday, and sick time and leave plans• Onsite childcare (Ames, Iowa)• Flexible Spending Accounts• Various voluntary benefits and discounts• Employee Assistance Program• Wellbeing Program

Original Posting Date: July 1, 2024

Posting Close Date:July 15, 2024

Job Requisition Number:R14968

By focusing on the future and providing the best student experience possible, Iowa State attracts students and faculty who want to make a difference. With a comprehensive land-grant mission of education, research, extension and outreach, we produce scholars whose ideas change the world. And through Innovate at Iowa State , we provide innovative and entrepreneurial opportunities for students of all backgrounds. Located just 30 minutes north of Des Moines, the city of Ames was recently named one of the Top 10 cities in the U.S. for campus life and career opportunities.

Iowa State University is a welcoming, global, and culturally diverse community of students, faculty, and staff. Campus community members have a wide range of backgrounds and experiences and are committed to engaging with each other respectfully as outlined in the university's Principles of Community (https://www.iastate.edu/diversity-and-inclusion/principles-community) . Iowa State recognizes that diverse intellectual and philosophical perspectives are vital to innovation, critical thinking skills, and a dynamic academic community that fosters the land-grant ideals of putting science, technology, and human creativity to work.

All offers of employment, oral and written, are contingent upon the university’s verification of credentials and other information required by federal and state law, ISU policies/procedures, and may include the completion of a background check and/or a consumer credit check.

Iowa State University is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, genetic information, national origin, marital status, disability, or protected veteran status and will not be discriminated against. Inquiries can be directed to the Office of Equal Opportunity, 3410 Beardshear Hall, 515 Morrill Road, 515 294-7612, email eooffice@iastate.edu .

If you have questions about the application process please email employment@iastate.edu or call 515-294-4800 or Toll-Free at 1-877-477-7485 . Iowa State University provides reasonable accommodations to applicants and employees with disabilities. Applicants with questions about access or requiring a reasonable accommodation for any part of the application or hiring process should email employment@iastate.edu or call (515) 294-4800 or Toll-Free: (877) 477-7485 . TTY users are welcome to use the Iowa Relay Service number by dialing 7-1-1 or (800) 735-2942 .

General ISU compensation information can be found on the University Human Resources (https://www.hr.iastate.edu/careers/compensation) website. Please note that this is only a list of ranges and individuals will be paid commensurate with qualifications.

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